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The study was based only on data from the published literature, did not allow for prospective or randomized controlled trials, and did not explore the direct associations between drug penetration ratios and adverse fetal or neonatal outcomes

The particle-mesh Ewald method 60 was employed to calculate long-range electrostatic interactions, whereas a smooth (10-12 ) cutoff was applied to treat van der Waals (vdW) interactions

Cells were detached using 0.25% trypsin-EDTA, collected by centrifugation at a speed of 1000 g for 5 min, and resuspended in PBS

10.3389/fimmu.2024.1435139 72 LuQ.ShaoN.FangZ.OuyangZ.ShenY.YangR.et al (2025)